ceesdekker No Further a Mystery

ceesdekker No Further a Mystery

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‘Of course, that's about suitable. I hunt for a physical knowledge of biological methods inside of a base-up way. I think you could possibly distinguish three traces of investigation in my group for the time being. The initial worries chromosome composition: How will you have a metre-prolonged DNA polymer folded and organised in this type of microscopic cell? We've got developed visualisation procedures that let us to check how, for instance, SMC proteins loop DNA (movie on Youtube) to be able to Develop up chromosomes.

You often become involved in discussions about science and religion. You've got also written various publications on the subject. Don’t you believe at some point We are going to know almost everything and that God’s purpose will likely be around?

Multicolor imaging on the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins

Since 2000, Dekker has shifted the principle focus of his perform to biophysics exactly where he scientific tests the properties of single biomolecules and cells using the instruments of nanotechnology. This change of area was driven by his fascination for that remarkable operating of Organic molecular buildings, in addition to by the extended-expression point of view that many intriguing discoveries might be predicted During this field.[5] Present lines of analysis in his biophysics group are while in the areas of:[6]

2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initial at any time examine from the dynamics DNA supercoils and the invention of supercoil hopping

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes

Lots of related developments followed, where our group established different transistor variants like single-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into smaller evidence-of-theory electronic circuits.

Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation

Imagine if, as opposed to utilizing common best-down silicon electronics, transistors could be designed from the bottom up applying single natural and organic molecules since the switching elements? This idea, which turned the basis of currently’s discipline of molecular electronics, first emerged from the 1970s.

There was a single dilemma while — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at the single-molecule level, conducting polymers were truly not these kinds of wonderful conductors, which was somewhat disappointing. We Consequently broadened our perspective to try to discover far more promising molecules.

‘The concept There's this type of matter to be a beginning, a large bang, is previously a fascinating signpost to consider that there was a creator. But much more normally, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.

Later on we spoke all over again briefly simply because Dekker felt that our discussion of his faith promptly turned purely philosophical, Whilst Additionally, it concretely will help him in his get the job done.

Enable’s first appear back in the meanwhile any time you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.

2004, discovery of recent physics in translocation of ceesdekker.net DNA by way of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and 1st single-molecule analyze of DNA translocation by a restriction-modification enzyme.